Medical Issues
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- What is PH?
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Clinical References
Primary Pulmonary Hypertension
Primary pulmonary hypertension (PPH) is a rare disease characterized by elevated pulmonary artery pressure with no apparent cause. PPH is also termed precapillary pulmonary hypertension or, more recently, idiopathic pulmonary arterial hypertension (IPAH). The term IPAH is now the preferred term for pulmonary arterial hypertension of unknown etiology; thus, IPAH represents pulmonary vascular disease with a spectrum of clinical presentations.
Secondary Pulmonary Hypertension
Pulmonary hypertension (PH) defined as a mean pulmonary arterial (PA) pressure of greater than 25 mm Hg at rest or greater than 30 mm Hg during exercise, is characterized by a progressive and sustained increase in pulmonary vascular resistance that eventually leads to right ventricular (RV) failure. Pulmonary hypertension is a life-threatening condition if untreated; treatment success rates vary based on etiology.
Current Guidelines and Expert Consenus:
A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association Developed in Collaboration With the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association.
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation.
European Society of Cardiology Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension
Guidelines published by The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT).
European Society of Cardiology Heart Failure Association Standards for Delivering Heart Failure Care
This document aims to summarize the key elements which should be involved in, as well as some more desirable features which can improve the delivery of care in a HF management programme, while bearing in mind that the specifics of the service may vary from site to site.
Self-care Management of Heart Failure: Practical Recommendations From the Patient Care Committee of the Heart Failure Association of the European Society of Cardiology
This paper summarizes the available evidence, promotes self-care management, and aims to provide practical advice for health professionals delivering care to HF patients. It also defines avenues of research to optimize self-care strategies in a number of key areas to derive further benefits.
ACCF/ASE/AHA/ASNC/HFSA/HRS/SCAI/SCCM/SCCT/SCMR 2011 Appropriate Use Criteria for Echocardiography
A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Society of Echocardiography, American Heart Association, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Critical Care Medicine, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance Endorsed by the American College of Chest Physicians
Diagnosis:
Pulmonary Disorders - Approach to the Patient With Pulmonary Symptoms - Dyspnea
The Merck Manual for Healthcare Professionals
Approach to Leg Edema of Unclear Etiology
Medscape, 03/14/2006
Early Diagnosis and Treatment of Pulmonary Arterial Hypertension
Medscape, 06/29/2005
Screening, Early Detection, and Diagnosis of Pulmonary Arterial Hypertension
ACCP Evidence-Based Clinical Practice Guidelines
Chest, July 2004
Failure of Medical Therapy in Pulmonary Arterial Hypertension - Is There an Alternative Diagnosis?
Chest, June, 2009
Treatment:
Perspectives on the Optimal Management of Pulmonary Arterial Hypertension
Medscape, April 2011
Management of PAH: When and How to Use IV Agents
Medscape, August 2011
Striving to Optimize Individual Patient Outcomes in Pulmonary Arterial Hypertension
Medscape, April 2011
Testing:
Hemodynamic Assessment of Pulmonary Hypertension: Echocardiography and Cardiac Catheterization
Medscape, 12/17/2007
J Am Coll Cardiol, 2006
Computed Tomography Angiography in Pulmonary Hypertension
IMAJ, February, 2008
MRI - One-Stop Shop for the Comprehensive Assessment of Pulmonary Arterial Hypertension?
Chest, July, 2007
AJR, 2007
Clinical Trials:
This web page provides several search tools to assist in locating current clinical trials.
Search Scientific Literature:
PubMed comprises more than 19 million citations for biomedical articles from MEDLINE and life science journals. Citations may include links to full-text articles from PubMed Central or publisher web sites.*
HighWire Press is a division of the Stanford University Libraries.” “HighWire Press hosts the largest repository of free full-text life science articles in the world, with 1,955,861 articles available without subscription.*
Medscape offers specialists, primary care physicians, and other health professionals the Web's most robust and integrated medical information and educational tools.*
UpToDate is an evidence based, peer reviewed information resource - available via the Web, desktop computer, and PDA. It is the largest clinical community in the world dedicated to synthesizing knowledge for clinicians and patients.*
*Individual descriptions quoted from respective websites.
October 2011 - Page Reviewed and Updated.
In The News
- November 27, 2011
- Pulmonary Hypertension: Screening and Evaluation in Scleroderma
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