- Adcirca® FAQ
- BiPAP / CPAP
- Calcium Channel Blockers
- Endothelin Receptor Antagonists
- Epoprostenol for Injection
- Epoprostenol sodium
- Inhaled Treprostinil
- Nitric Oxide
- Oral Remodulin®
- Orral treprostinil
- Other Drugs and Treatments
- Phosphodiesterase type-5 Inhibitor
- Sildenafil Citrate
- Sitaxsentan Sodium
- Tracleer® FAQ
- Under FDA Review
Tracleer was the first oral medication approved for treatment of PAH. It is a dual endothelin receptor antagonist, meaning that it blocks both endothelin receptors.
Fda approval date
- Tracleer may cause liver damage; therefore monitoring liver enzyme levels is necessary. This is done by a blood test every month.
- Tracleer may cause birth defects; therefore, it is essential that patients on Tracleer are not pregnant and don't become pregnant. Monthly pregnancy tests must be obtained.
- Oral, injected and implanted contraceptives may not be reliably effective because Tracleer may alter their metabolism in a way that reduces the effectiveness of hormonal contraceptives, so these methods must be supplemented by other methods or barrier methods must be used. Therefore, it is important for patients to consult with a gynecologist or other physician knowledgeable about contraceptives.
Headache, sore throat, and flushing are reported by some users.
Tracler has been shown to offer these important benefits to people with PAH:
- Tracleer can improve symptoms and the ability to perform normal daily activities.
- Tracleer can improve the worsening of symptoms.
- Tracleer can lower high blood pressure in the lungs.
- Tracleer can enable the heart to pump blood more effectively
Page Reviewed/Edited: October 2010
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- June 7, 2012
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- December 7, 2011
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- EMA Reviewing Drug Class That Includes Pfizer’s Thelin
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- FDA Warns Actelion Unit On Post-Marketing Drug Report Failures
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- Funding of Tracleer will bring relief to Kiwi PAH sufferers
- August 14, 2009
- FDA Approves Bosentan for Treating Early-Stage PAH