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We are in the process of updating our medical section (Feb. 2006). All approved PAH treatments are listed, but you may not find details relating to how the drugs work on this site at this time. In the short term, we have provided links to the producer's website.
Prostaglandin
is a steroid that is produced naturally in the body in a normally
healthy person. It causes blood vessels in the lungs to relax and
allow blood to flow through them more easily. People with pulmonary
hypertension do not produce enough prostaglandin, so the blood vessels
in the lungs are constricted. Prostacyclin, also known as epoprostenol,
is a synthetic substance that is administered to remedy this deficiency.
Prostacyclin therapy was initially used as a bridge to lung transplantation
although it has also emerged as an alternative to transplantation
in some patients. Although research continues on other forms of
prostacyclin, it is currently available in these forms:
Flolan®
Remodulin®
Ventavis®
Recent items from the PHCentral Newsroom:
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Lung Medicine Decision ‘Could Cost Lives’
(The Herald) -- Hundreds of patients with a rare lung disorder could die and a Scottish centre of excellence in treating the condition could be threatened as a result of a decision by the medicines regulator for England and Wales, according to campaigners.
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