PHCentral RSS - rss FIRE feed Wed, 28 Jan 2015 20:01:42 GMT Concentric remodelling preserves right ventricular function in PAH January 30, 2015 SERAPHIN: Macitentan linked to decreased hospitalization risk{9b934593-7f30-4102-b8ff-c9e2c6b34e11}/seraphin-macitentan-linked-to-decreased-hospitalization-risk January 29, 2015 Why Sleep Soothes The Flu January 28, 2015 Takayasu Arteritis-associated Pulmonary Hypertension January 28, 2015 A comparison of the predictive accuracy of three screening models for AH in systemic sclerosis January 27, 2015 Peripheral muscles weakened in PAH patients January 26, 2015 The Flavonoid Quercetin Reverses Pulmonary Hypertension in Rats January 25, 2015 Idiopathic PA Hypertension Responds Variably to Vasodilators January 25, 2015
"Not all patients with seeming IPAH are alike," Dr. David Langleben, of McGill University, Montreal, Quebec, told Reuters Health by email. "The acute vasodilator responders are a truly distinct group. This group should probably be a separate subcategory in the classification of IPAH."]]>
CT measures can refine PAH prognosis January 24, 2015 Early Screening Methods for Pulmonary Arterial Hypertension in Systemic Sclerosis Evaluated in New Study January 24, 2015 Arthritis Research & Therapy.]]> New Treatments Haven't Lowered Anesthesia Risks for Children with Pulmonary Hypertension January 23, 2015 Asthma Linked to New-Onset Sleep Apnea January 21, 2015 Seasonal Influenza Vaccine Only 23% Effective This Year January 20, 2015 Ascendis to Start Phase 1 Study of PAH Treatment January 19, 2015 Notch Activation of Ca2+ Signaling Mediates Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. January 18, 2015 Pacific Therapeutics CEO Provides Updates About Therapy For Idiopathic Pulmonary Fibrosis January 18, 2015 Bellerophon Therapeutics (BLPH) Files $69M IPO$69M+IPO/10162123.html January 18, 2015 Effects of Epoprostenol on Right Ventricular Hypertrophy and Dilatation in Pulmonary Hypertension January 17, 2015 Exercise Pathophysiology in Patients With Primary Pulmonary Hypertension January 17, 2015 Pulmonary Arterial Hypertension Medications Studied for Drug Interactions January 16, 2015 Pulmonary hypertension in idiopathic pulmonary fibrosis does not influence six-minute walk distance January 16, 2015 [..]
Conclusions: Our data suggested that 6MWD does not differ between IPF patients with or without PH. Thus, 6MWD should not be used as a surrogate endpoint in clinical study in patients affected by IPF and PH.]]>
Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model. January 15, 2015 Ascendis Pharma A/S Announces Initiation of a Phase 1 Single Ascending Dose Study of TransCon Treprostinil January 14, 2015
TransCon Treprostinil has been designed as an inert prodrug that enables a sustained release of unmodified treprostinil in circulation following a once-daily self-administered subcutaneous injection. TransCon Treprostinil is intended to produce a pharmacokinetic profile comparable to continuously infused prostacyclins, with the benefit of a more convenient route of administration, while avoiding the infusion site pain and risk of bloodstream infections associated with currently marketed infused prostacyclin therapies...]]>
Survival of adults with systemic sclerosis following lung transplantation: A nationwide cohort study. January 14, 2015 Pharmacokinetic interactions among imatinib, bosentan and sildenafil, and their clinical implications in severe pulmonary arterial hypertension. January 13, 2015
Arena Pharmaceuticals Initiates Phase 2 Clinical Trial Evaluating Ralinepag for Pulmonary Arterial Hypertension January 12, 2015
"An intriguing component of this compound is the smooth peak-to-trough ratio, which may potentiate efficacy and minimize toxicity relative to currently available therapies," said Lewis J. Rubin, M.D., Emeritus Professor of Medicine at University of California, San Diego, School of Medicine. "This clinical trial should help to further elucidate how ralinepag's intrinsic properties translate to its efficacy and safety profile."

This 22-week, randomized, double-blind and placebo-controlled Phase 2 trial will..]]>
Pulmonary Hypertension in Chronic Lung Diseases January 11, 2015 Role of BNP and Echo measurement for pulmonary hypertension recognition in patients with interstitial lung disease: an algorithm application model January 11, 2015 United Therapeutics and DEKA Sign Agreement for New PAH Remodulin Delivery System January 10, 2015 Modified Potts Shunt in an adult with pulmonary arterial hypertension and recurrent syncope – three-year follow-up January 10, 2015 Flu Season 2015: Influenza In US ‘Widespread,’ But Fear May Outpace Threat January 8, 2015 Could a National PH Registry Improve Research and Treatment in America? January 7, 2015 Health Talk: Know the signs and symptoms of COPD,0,5417500.story January 6, 2015 Pulmonary Arterial Hypertension in the US: How Much Does it Cost? January 5, 2015 Medtronic Submits Drug Delivery System to FDA to Complement United Therapeutics’ PAH Treatment January 4, 2015 Diagnosis, Assessment, and Treatment of Non-Pulmonary Arterial Hypertension Pulmonary Hypertension January 4, 2015 Actelion Submits New Drug for Pulmonary Arterial Hypertension to FDA January 3, 2015 Absence of the calcium-binding protein, S100A1, confers pulmonary hypertension in mice associated with endothelial dysfunction and apoptosis January 3, 2015