PHCentral RSS - rss http://phcentral.org FIRE feed Tue, 3 Mar 2015 11:03:22 GMT Why Heart Rate Matters http://www.phcentral.org/news/5605 http://www.heartratematters.com/why-heart-rate-matters/ March 2, 2015 ≥19% INCREASE in the risk of all-cause mortality in patients with left ventricular dysfunction (LVEF ≤ 40%)
≥25% INCREASE in the risk of the composite outcome of CV death or hospital stay for worsening HF in patients with left ventricular dysfunction (LVEF ≤ 40%)]]>
Role for Telomerase in Pulmonary Hypertension http://www.phcentral.org/news/5604 http://circ.ahajournals.org/content/131/8/742.full March 1, 2015 SteadyMed Raises $12.2M to Advance PAH Therapy http://www.phcentral.org/news/5603 http://pulmonaryhypertensionnews.com/2015/02/19/steadymed-raises-12-2m-to-advance-pah-therapy/ March 1, 2015 CDC Says Influenza Vaccine Only 18% Effective This Year http://www.phcentral.org/news/5602 http://www.medscape.com/viewarticle/840557 February 28, 2015 Adempas Approved in Japan for the Treatment of Pulmonary Arterial Hypertension http://www.phcentral.org/news/5601 http://www.finchannel.com/index.php/component/k2/item/40342-adempas-approved-in-japan-for-the-treatment-of-pulmonary-arterial-hypertension February 28, 2015 Pregnancy in PAH Patients Focus of Recent Study http://www.phcentral.org/news/5600 http://pulmonaryhypertensionnews.com/2015/02/26/pulmonary-arterial-hypertension-an-absolute-contraindication-in-pregnancy/ February 26, 2015 PH Patients Given Higher Lung Transplant Priority with Revised LAS http://www.phcentral.org/news/5599 http://pulmonaryhypertensionnews.com/2015/02/24/ph-patients-given-higher-lung-transplant-priority-with-revised-las/ February 25, 2015 Ultrasound-accelerated thrombolysis may improve pulmonary embolism outcomes http://www.phcentral.org/news/5598 http://www.2minutemedicine.com/ultrasound-accelerated-thrombolysis-may-improve-pulmonary-embolism-outcomes/ February 24, 2015 CTEPH Patients Are More Accurately Assessed During Exercise, Study Shows http://www.phcentral.org/news/5597 http://lungdiseasenews.com/2015/02/20/cteph-patients-are-more-accurately-assessed-during-exercise-study-shows/ February 23, 2015 Treating pulmonary hypertension in pediatrics. http://www.phcentral.org/news/5596 http://www.ncbi.nlm.nih.gov/pubmed/25665593 February 22, 2015 Ongoing Clinical Trial: Efficacy of Bosentan in Exercise-Induced PAH Secondary to Congenital Heart Disease http://www.phcentral.org/news/5595 http://pulmonaryhypertensionnews.com/2015/02/12/ongoing-clinical-trial-efficacy-of-bosentan-in-exercise-induced-pah-secondary-to-congenital-heart-disease/ February 22, 2015 Up-regulation of Hexokinase1 in the Right Ventricle of Monocrotaline Induced Pulmonary Hypertension http://www.phcentral.org/news/5594 http://www.medscape.com/viewarticle/837905 February 21, 2015 Radionuclide angiography-assessed RVEF predicts PAH outcomes http://www.phcentral.org/news/5593 http://www.news-medical.net/news/20150213/Radionuclide-angiography-assessed-RVEF-predicts-PAH-outcomes.aspx February 21, 2015 Recent IPF Study Addresses Emotional and Physical Impact on Both Patients and Caregivers http://www.phcentral.org/news/5592 http://pulmonaryhypertensionnews.com/2015/02/20/recent-ipf-study-addresses-emotional-and-physical-impact-on-both-patients-and-caregivers/ February 20, 2015 Right Ventricular Remodeling Might be Adaptative in Idiopathic Pulmonary Arterial Hypertension http://www.phcentral.org/news/5591 http://pulmonaryhypertensionnews.com/2015/02/18/right-ventricular-remodeling-might-be-adaptative-in-idiopathic-pulmonary-arterial-hypertension/ February 19, 2015 Effects of chrysin (5,7-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension http://www.phcentral.org/news/5590 http://7thspace.com/headlines/504067/effects_of_chrysin_57_dihydroxyflavone_on_vascular_remodeling_in_hypoxia_induced_pulmonary_hypertension_in_rats.html February 18, 2015 The Lasting Legacy of Fen-Phen http://www.phcentral.org/news/5589 http://www.lawyersandsettlements.com/articles/pph_class_action/pph-fen-phen-primary-pulmonary-hypertension-23-20452.html#.VONbdGd0xbQ February 17, 2015 ]]> Researchers Study PAH in Rheumatoid Arthritis Versus Idiopathic PAH http://www.phcentral.org/news/5588 http://pulmonaryhypertensionnews.com/2015/02/13/researchers-study-pah-rheumatoid-arthritis-versus-idiopathic-pah/ February 16, 2015 Smoking is even MORE dangerous than we thought http://www.phcentral.org/news/5587 http://www.dailymail.co.uk/health/article-2955391/Smoking-dangerous-thought-Scientists-link-habit-five-extra-diseases-bringing-total-26.html February 16, 2015 ]]> Bosentan Improves Pulmonary Hypertension Secondary to IPF in Individual Case Study http://www.phcentral.org/news/5586 http://pulmonaryhypertensionnews.com/2015/02/10/bosentan-improves-pulmonary-hypertension-secondary-to-ipf/ February 15, 2015 Native T1 myocardial tissue characterisation in patients with pulmonary hypertension: findings from International T1 Multicentre Study http://www.phcentral.org/news/5585 http://paperity.org/p/58844297/native-t1-myocardial-tissue-characterisation-in-patients-with-pulmonary-hypertension February 15, 2015 EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-?1 signaling http://www.phcentral.org/news/5584 http://www.jci.org/articles/view/77656 February 14, 2015 Pulmonary Arterial Hypertension Could Improve with Calorie Restriction http://www.phcentral.org/news/5583 http://pulmonaryhypertensionnews.com/2015/02/04/pulmonary-arterial-hypertension-could-improve-with-calorie-restriction/ February 14, 2015 Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension http://www.phcentral.org/news/5582 http://circ.ahajournals.org/content/early/2015/01/15/CIRCULATIONAHA.114.008750.short February 13, 2015 Survival in rheumatoid arthritis-associated pulmonary arterial hypertension http://www.phcentral.org/news/5581 http://onlinelibrary.wiley.com/doi/10.1111/resp.12464/abstract February 12, 2015
Compared with IPAH patients, RA-PAH patients have an older age of onset and lower baseline mPAP. RA-PAH patients have comparable survival to IPAH patients.]]>
Suppression of the TRPC1 Gene Could Prevent Hypoxia-induced Pulmonary Hypertension http://www.phcentral.org/news/5580 http://pulmonaryhypertensionnews.com/2015/01/16/suppression-of-the-trpc1-gene-could-prevent-hypoxia-induced-pulmonary-hypertension/ February 11, 2015 Findings from this study confirmed that RVSP and the expressions of TRPCs were significantly enhanced in a murine model of hypoxia-induced PAH and were markedly suppressed after siRNA-TRPC1 treatment. The authors’ concluded that these findings may offer a therapeutic option for the treatment of patients with PAH refractory to conventional regimens.]]> ERS Pulmonary Hypertension Research Award http://www.phcentral.org/news/5579 http://www.ersnet.org/ers-funding/awards/item/4940-ph-research-award.html February 10, 2015 Overview of pulmonary hypertension in adults http://www.phcentral.org/news/5578 http://www.uptodate.com/contents/overview-of-pulmonary-hypertension-in-adults February 9, 2015 ]]> Increasing Number of Promising PAH Drug Targets Are On the Horizon, According to Study http://www.phcentral.org/news/5577 http://pulmonaryhypertensionnews.com/2015/02/06/study-reviews-novel-molecular-target-advancements-for-the-treatment-of-pulmonary-arterial-hypertension/ February 9, 2015 West Michigan woman first in world to get life-saving heart device http://www.phcentral.org/news/5576 http://www.mlive.com/news/grand-rapids/index.ssf/2015/02/west_michigan_woman_first_in_w.html February 8, 2015 SteadyMed Raises $12.2 Million To Advance PAH Therapy http://www.phcentral.org/news/5575 http://pulmonaryhypertensionnews.com/2015/02/03/steadymed-raises-12-2-million-to-advance-pah-therapy/ February 8, 2015 Bellerophon Therapeutics (BLPH) Plans to Raise $60 Million in February 13th IPO http://www.phcentral.org/news/5573 http://tickerreport.com/banking-finance/406794/bellerophon-therapeutics-blph-plans-to-raise-60-million-in-february-13th-ipo/ February 7, 2015 Networks Reveal the Connections of Disease http://www.phcentral.org/news/5574 https://www.quantamagazine.org/20150129-networks-reveal-the-connections-of-disease/ February 7, 2015 Researchers Find That Physical Examination is Unreliable in Detecting Pulmonary Hypertension http://www.phcentral.org/news/5572 http://pulmonaryhypertensionnews.com/2015/02/05/researchers-find-that-physical-examination-is-unreliable-in-detecting-pulmonary-hypertension/ February 6, 2015 Survival advantages of excess body mass index in patients with idiopathic pulmonary arterial hypertension. http://www.phcentral.org/news/5571 http://www.ncbi.nlm.nih.gov/pubmed/25643438 February 5, 2015
The Kaplan-Meier survival curves for the three BMI categories demonstrated that the overweight and obese group had a significantly higher survival rate than the normal weight and underweight groups (log-rank test, P = 0.027, P = 0.000, respectively). In a stepwise forward regression, lower BMI, higher WHO functional class, lower cardiac index, smaller LVEDDs and absence of targeted medication remained independent predictors of mortality.]]>
New molecular targets of pulmonary vascular remodeling in pulmonary arterial hypertension: importance of endothelial communication. http://www.phcentral.org/news/5570 http://www.ncbi.nlm.nih.gov/pubmed/25644906 February 4, 2015 SSc-PH May Show Increase in Damaged Blood Vessel Biomarker EMPs http://www.phcentral.org/news/5568 http://pulmonaryhypertensionnews.com/2015/02/02/ssc-ph-may-show-increase-in-damaged-blood-vessel-biomarker-emps/ February 3, 2015 Germany: Interview with a patient suffering from pulmonary arterial hypertension http://www.phcentral.org/news/5569 http://pvrifiles.s3.amazonaws.com/PVRI_Publication/PVRI_Chronicle/Vol 2/TOC separate articles/Sommer patient interview.pdf February 3, 2015 Calorie Restriction Attenuates Monocrotaline-induced Pulmonary Arterial Hypertension in Rats. http://www.phcentral.org/news/5567 http://www.ncbi.nlm.nih.gov/pubmed/25636073 February 2, 2015