PHCentral RSS - rss http://phcentral.org FIRE feed Fri, 22 May 2015 20:05:23 GMT Arginine metabolic endotypes in pulmonary arterial hypertension http://www.phcentral.org/news/5741 http://www.jstor.org/stable/10.1086/679720 May 22, 2015 Celsion Corporation Announces TheraSilence Technology Effective in Model of Potential Severe Occlusive PAH Treatment http://www.phcentral.org/news/5737 http://pulmonaryhypertensionnews.com/2015/05/19/celsion-corporation-announces-therasilence-technology-effective-model-potential-severe-occlusive-pah-treatment/ May 22, 2015 Impact of diabetes in patients with pulmonary hypertension http://www.phcentral.org/news/5742 http://www.jstor.org/stable/10.1086/679705 May 22, 2015 Pulmonary hypertension associated with heart failure with preserved ejection fraction: acute hemodynamic effects of inhaled iloprost http://www.phcentral.org/news/5739 http://www.jstor.org/stable/10.1086/679725 May 22, 2015 Acute hemodynamic effects of nebulized iloprost via the I-neb Adaptive Aerosol Delivery system in pulmonary hypertension http://www.phcentral.org/news/5740 http://www.jstor.org/stable/10.1086/679722 May 21, 2015 ATS: Combo Tx Cuts Admissions in PAH http://www.phcentral.org/news/5736 http://www.medpagetoday.com/MeetingCoverage/ATS/51603 May 21, 2015 Association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-?) gene and systemic sclerosis. http://www.phcentral.org/news/5738 http://www.ncbi.nlm.nih.gov/pubmed/25986483 May 20, 2015
A PPARG variant is associated with susceptibility to SSc, consistent with a role of PPAR-γ in the pathogenesis of SSc.-]]>
Mitral Valve Surgery Identified As Potential Treatment For PAH Secondary to Mitral Valve Disease http://www.phcentral.org/news/5735 http://pulmonaryhypertensionnews.com/2015/05/18/mitral-valve-surgery-identified-potential-pulmonary-arterial-hypertension-treatment/ May 20, 2015 ATS 2015 Denver http://www.phcentral.org/news/5734 http://conference.thoracic.org/2015/program/ May 19, 2015 Read through the Abstracts here.
 

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Red Blood Cell Distribution Width (RDW) can predict Vasolilator Response http://www.phcentral.org/news/5733 http://www.ncbi.nlm.nih.gov/pubmed/25966828 May 18, 2015 Inhaler Ban Boosts Costs for People With Asthma http://www.phcentral.org/news/5732 http://www.medscape.com/viewarticle/844490 May 17, 2015 Further data on selexipag (Uptravi) and macitentan (Opsumit) to be presented at American Thoracic Society (ATS) Conference 2015 http://www.phcentral.org/news/5731 http://finance.yahoo.com/news/further-data-selexipag-uptravi-macitentan-050201128.html May 17, 2015 You May Be Getting Up to Pee At Night Because of Sleep Apnea http://www.phcentral.org/news/5730 http://www.huffingtonpost.com/stanford-center-for-sleep-sciences-and-medicine/you-may-be-getting-up-to-pee-at-night-because-of-sleep-apnea_b_7206750.html May 16, 2015 Harpoon Medical Enrolls Initial Three Patients in Early Feasibility Study of Its Repair System for off-Pump, Minimally Invasive Treatment of Mitral Valve Regurgitation http://www.phcentral.org/news/5729 http://www.businesswire.com/news/home/20150507006235/en/Harpoon-Medical-Enrolls-Initial-Patients-Early-Feasibility#.VVc1YoGuqSo May 16, 2015 Patients with scleroderma at highest risk for pulmonary arterial hypertension http://www.phcentral.org/news/5728 http://www.healio.com/rheumatology/scleroderma/news/online/{2f461db5-6c2e-4951-971c-0424d2fe540c}/patients-with-scleroderma-at-highest-risk-for-pulmonary-arterial-hypertension May 15, 2015 Pediatric Pulmonary Hypertension Registry Receives NIH Funding http://www.phcentral.org/news/5727 http://pulmonaryhypertensionnews.com/2015/05/12/pediatric-pulmonary-hypertension-registry-receives-nih-funding/ May 14, 2015 SteadyMed seeks orphan drug designation from FDA for Trevyent to treat PAH http://www.phcentral.org/news/5726 http://itsoftware.pharmaceutical-business-review.com/news/steadymed-seeks-orphan-drug-designation-from-fda-for-trevyent-to-treat-pah-110515-4573487 May 13, 2015
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An excellent result of surgical treatment in patients with severe pulmonary arterial hypertension following mitral valve disease http://www.phcentral.org/news/5725 http://7thspace.com/headlines/508529/an_excellent_result_of_surgical_treatment_in_patients_with_severe_pulmonary_arterial_hypertension_following_mitral_valve_disease.html May 12, 2015 Bellerophon Therapeutics Creates PH-Focused Scientific Advisory Board For INOpulse Programs http://www.phcentral.org/news/5724 http://pulmonaryhypertensionnews.com/2015/05/11/bellerophon-therapeutics-creates-ph-focused-scientific-advisory-board-inopulse-programs/ May 11, 2015 Researchers Developing Registry for Pediatric Pulmonary Hypertension http://www.phcentral.org/news/5723 http://www.research.chop.edu/researchers-developing-registry-pediatric-pulmonary-hypertension May 10, 2015 Bosentan in pulmonary hypertension secondary to unilateral absence of a pulmonary artery http://www.phcentral.org/news/5722 http://www.internationaljournalofcardiology.com/article/S0167-5273(15)00972-9/abstract May 10, 2015 Ascendis Pharma Releases Results of Phase 1 Study of PAH Therapy TransCon Treprostinil http://www.phcentral.org/news/5721 http://pulmonaryhypertensionnews.com/2015/04/30/ascendis-pharma-reveals-results-phase-1-study-pulmonary-arterial-hypertension-therapy-transcon-treprostinil/ May 9, 2015 What is new about Rio? http://www.phcentral.org/news/5720 http://erj.ersjournals.com/content/45/5/1211.short May 9, 2015 European Respiratory Journal includes the results of three different studies of riociguat, a soluble guanylate cyclase stimulator, for the treatment of pulmonary hypertension. As the first drug in a novel class for the treatment of pulmonary hypertension, riociguat has raised hopes of an expanded drug armamentarium against the still incurable diseases of pulmonary arterial hypertension (PAH) and surgically inaccessible (or persistent post-operative) chronic thromboembolic pulmonary hypertension (CTEPH). Two of these studies are long-term extension studies from pivotal phase III trials: CHEST-1 (Chronic Thromboembolic Pulmonary Hypertension Soluble Guanylate Cyclase–Stimulator Trial 1) and PATENT-1 (Pulmonary Arterial Hypertension Soluble Guanylate Cyclase–Stimulator Trial 1). The third study (PATENT PLUS) studied the safety and efficacy of the combination of riociguat and the phosphodiesterase (PDE)-5 inhibitor, sildenafil.]]> SteadyMed Submits Application for Orphan Drug Designation for Trevyent(R) For Pulmonary Arterial Hypertension http://www.phcentral.org/news/5718 http://globenewswire.com/news-release/2015/05/07/733409/10133186/en/SteadyMed-Submits-Application-for-Orphan-Drug-Designation-for-Trevyent-R-For-Pulmonary-Arterial-Hypertension.html May 8, 2015 Genetic and phenotypic differentiation of an Andean intermediate altitude population. http://www.phcentral.org/news/5719 http://www.ncbi.nlm.nih.gov/pubmed/25948820 May 8, 2015 Iptakalim attenuates hypoxia-induced pulmonary arterial hypertension in rats by endothelial function protection. http://www.phcentral.org/news/5717 http://www.spandidos-publications.com/10.3892/mmr.2015.3695 May 7, 2015 3D Human Lung Tissue Cultures Used to Test COPD Therapeutics http://www.phcentral.org/news/5716 http://lungdiseasenews.com/2015/05/05/3d-human-lung-tissue-cultures-used-test-copd-therapeutics/ May 6, 2015 PhaseBio Announces Promising Pre-Clinical Results for PB1046 in Models of Duchenne Muscular Dystrophy http://www.phcentral.org/news/5715 http://globenewswire.com/news-release/2015/04/22/726983/10130090/en/PhaseBio-Announces-Promising-Pre-Clinical-Results-for-PB1046-in-Models-of-Duchenne-Muscular-Dystrophy.html May 4, 2015 Latest Clinical Study Finds Ventripoint VMS(TM) Offers Consistent and Accurate Results Regardless of Examiner http://www.phcentral.org/news/5714 http://www.digitaljournal.com/pr/2534275 May 3, 2015 Long-Term Selexipag Phase 3 Clinical Trial Results For PAH Recently Presented http://www.phcentral.org/news/5713 http://pulmonaryhypertensionnews.com/2015/04/23/long-term-selexipag-phase-3-clinical-trial-results-pah-recently-presented/ May 3, 2015 Pulmonary arterial hypertension market expected to reach USD 5.19 billion globally in 2020 outlined in new market research report http://www.phcentral.org/news/5712 http://www.whatech.com/market-research-reports/press-release/medical/55962-pulmonary-arterial-hypertension-market-expected-to-reach-usd-5-19-billion-globally-in-2020-outlined-in-new-market-research-report May 2, 2015 Serodus Files Patent Application in UK To Begin Pulmonary Hypertension Therapy Development http://www.phcentral.org/news/5711 http://pulmonaryhypertensionnews.com/2015/04/22/serodus-files-patent-application-uk-begin-pulmonary-hypertension-therapy-development/ May 2, 2015 Early Mortality Still a Factor in Systemic Sclerosis http://www.phcentral.org/news/5710 http://www.medpagetoday.com/MeetingCoverage/BSR/51297 May 1, 2015 Ascendis Pharma Reveals Results of Phase 1 Study of Pulmonary Arterial Hypertension Therapy TransCon Treprostinil http://www.phcentral.org/news/5709 http://pulmonaryhypertensionnews.com/2015/04/30/ascendis-pharma-reveals-results-phase-1-study-pulmonary-arterial-hypertension-therapy-transcon-treprostinil/ April 30, 2015 Multidisciplinary Approach Key to Management of Pregnant Pulmonary Hypertension Patients http://www.phcentral.org/news/5708 http://pulmonaryhypertensionnews.com/2015/04/29/multidisciplinary-approach-key-management-pregnant-pulmonary-hypertension-patients/ April 29, 2015 Researchers Find That Estrogen Receptor Alpha is Linked to Pulmonary Hypertension Development http://www.phcentral.org/news/5707 http://pulmonaryhypertensionnews.com/2015/04/28/researchers-find-that-estrogen-receptor-alpha-is-linked-to-pulmonary-hypertension-development/ April 28, 2015 Pulmonary Hypertension’s Link To Hepatic Cirrhosis Explored in New Study http://www.phcentral.org/news/5706 http://pulmonaryhypertensionnews.com/2015/04/27/pulmonary-hypertensions-link-hepatic-cirrhosis-explored-new-study/ April 27, 2015 Diastolic Pulmonary Gradient does not Predict Survival in Pulmonary Hypertension due to Left Heart Failure http://www.phcentral.org/news/5704 https://www.acc.org/latest-in-cardiology/articles/2015/04/14/10/07/diastolic-pulmonary-gradient-does-not-predict-survival-in-pulmonary-hypertension-due-to-left-heart-failure?w_nav=LC April 26, 2015 Salidroside Decreases Lung Pathology Associated with Pulmonary Arterial Hypertension http://www.phcentral.org/news/5703 http://pulmonaryhypertensionnews.com/2015/04/21/salidroside-decreases-lung-pathology-associated-pulmonary-arterial-hypertension/ April 26, 2015 Journal of Molecular and Cellular Cardiology.]]> Serology Helps Pinpoint Type of Scleroderma http://www.phcentral.org/news/5702 http://www.medpagetoday.com/Rheumatology/GeneralRheumatology/51159 April 25, 2015 Measures of Lung Function Sensitive to Comorbidity of Scleroderma http://www.phcentral.org/news/5705 http://sclerodermanews.com/2015/04/24/measures-lung-function-sensitive-comorbidity-scleroderma/ April 25, 2015 The Implantable Pediatric Artificial Lung http://www.phcentral.org/news/5701 http://www.ncbi.nlm.nih.gov/pubmed/25905495 April 24, 2015 DiscoveryBioMed, Inc. is developing a novel “dual action” small molecule monotherapy for all cystic fibrosis (CF) patients http://www.phcentral.org/news/5693 http://www.businesswire.com/news/home/20150414005091/en/DiscoveryBioMed-developing-“dual-action”-small-molecule-monotherapy#.VTJBW4GuqSo April 24, 2015 Early Decline in 6-minute Walk Test Distance Predicts Pulmonary Arterial Hypertension Deterioration http://www.phcentral.org/news/5696 http://pulmonaryhypertensionnews.com/2015/04/17/early-decline-6-minute-walk-test-distance-predicts-pulmonary-arterial-hypertension-deterioration/ April 23, 2015 Johns Hopkins iOS app helps clinicians learn to diagnose sleep disorders http://www.phcentral.org/news/5692 http://www.technologytell.com/apple/148697/johns-hopkins-ios-app-helps-clinicians-learn-diagnose-sleep-disorders/ April 23, 2015 Diet makes the differenice in broiler chicken - PH http://www.phcentral.org/news/5700 http://www.ncbi.nlm.nih.gov/pubmed/25900413 April 23, 2015 In a trial, different nutrition was tried and it turned out, that a protein-reduced and antioxidant enriched (co-encym Q10 and vitamine E) diet reduced death by PH in these animal. This shows at least, that nutrition could make a difference. If this would also apply to humans had would be difficult to find out.
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