PHCentral RSS - rss http://phcentral.org FIRE feed Sat, 28 May 2016 09:05:16 GMT Mast Therapeutics Announces Positive Interim Results from Phase 2 Trial in Select PH Patients http://www.phcentral.org/news/6227 http://pulmonaryhypertensionnews.com/2016/05/19/mast-therapeutics-presents-positive-interim-results-of-phase-2a-trial-of-air001-at-the-2016-ats-international-conference/ May 29, 2016 Benefits of Anticoagulant Use in PAH Largely Unknown and in Need of Study, ResearchersSay http://www.phcentral.org/news/6226 http://pulmonaryhypertensionnews.com/2016/05/20/benefits-of-anticoagulant-medication-in-pah-need-further-study/ May 28, 2016 Breakthrough could help sufferers of fatal lung disease http://www.phcentral.org/news/6225 http://medicalxpress.com/news/2016-05-breakthrough-fatal-lung-disease.html May 27, 2016 The Reviva Pharmaceuticals results were presented at the American Thoracic Society International Conference 2016 http://www.phcentral.org/news/6224 http://lungdiseasenews.com/2016/05/24/reviva-pharmaceuticals-presented-rp5063-preclinical-efficacy-results-for-pulmonary-arterial-hypertension-at-the-american-thoracic-society-conference-2016/ May 26, 2016 PAH Drug, Riociguat, Found Not to Alter the Effectiveness of Oral Contraceptives http://www.phcentral.org/news/6223 http://pulmonaryhypertensionnews.com/2016/05/24/riociguat-has-no-negative-effect-on-oral-contraceptives-in-pah-women-study-reports/ May 25, 2016 Speaker: Treatment of systemic lupus erythematosus should be flexible http://www.phcentral.org/news/6222 http://www.healio.com/rheumatology/lupus/news/online/{6c7e8294-e434-4e57-a45a-c84ab21bb5d3}/speaker-treatment-of-systemic-lupus-erythematosus-should-be-flexible May 25, 2016 Mast Therapeutics (MSTX) Reports Positive Interim Results From Second Phase 2a Study of AIR001 in Patients With HFpEF http://www.phcentral.org/news/6221 http://www.streetinsider.com/Corporate+News/Mast+Therapeutics+(MSTX)+Reports+Positive+Interim+Results+From+Second+Phase+2a+Study+of+AIR001+in+Patients+With+HFpEF/11633700.html May 24, 2016 MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in PAH http://www.phcentral.org/news/6220 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153780 May 23, 2016 Vascular BioSciences Presents New Data from Pulmonary Hypertension Studies at ATS 2016 http://www.phcentral.org/news/6219 http://pulmonaryhypertensionnews.com/2016/05/18/vascular-biosciences-make-six-presentations-american-thoracic-society-san-francisco-may-15-may-18/ May 21, 2016 Safety, efficacy, and clinical utility of macitentan in the treatment of pulmonary arterial hypertension http://www.phcentral.org/news/6218 https://www.dovepress.com/safety-efficacy-and-clinical-utility-of-macitentan-in-the-treatment-of-peer-reviewed-article-DDDT May 20, 2016 Actelion gets EU go-ahead for Uptravi in PAH http://www.phcentral.org/news/6217 http://www.pmlive.com/pharma_news/actelion_gets_eu_go-ahead_for_uptravi_in_pah_1024687 May 19, 2016 US trial tests machine that 'reconditions' lungs outside body http://www.phcentral.org/news/6216 http://www.foxnews.com/health/2016/05/18/us-trial-tests-machine-that-reconditions-lungs-outside-body.html May 18, 2016 Bayer Stops Phase II Adempas Study Due to Safety Issues http://www.phcentral.org/news/6215 http://www.zacks.com/stock/news/217358/bayer-stops-phase-ii-adempas-study-due-to-safety-issues May 17, 2016 ]]> PDE4 Inhibitor Identified in Study as New and Promising Treatment for Pulmonary Hypertension http://www.phcentral.org/news/6214 http://pulmonaryhypertensionnews.com/2016/05/13/pharmacological-profile-gpd-1116-inhibitor-phosphodiesterase-4/ May 16, 2016 More evidence for combination therapy benefits in PAH http://www.phcentral.org/news/6213 http://www.news-medical.net/news/20160506/More-evidence-for-combination-therapy-benefits-in-PAH.aspx May 15, 2016 CHEST, shows benefits for a range of individual clinical indicators, including 6-minute walk distance, functional class and haemodynamics.]]> Detailed digital human models could hold key to future clinical research http://www.phcentral.org/news/6212 http://medicalxpress.com/news/2016-05-digital-human-key-future-clinical.html May 14, 2016 Long-term improvement during tadalafil therapy in a patient with pulmonary hypertension secondary to pulmonary Langerhans cell histiocytosis http://www.phcentral.org/news/6211 http://www.respiratorycasereports.com/article/S2213-0071(16)30033-8/fulltext May 13, 2016 HIPPO-integrin Linked Kinase Crosstalk Controls Self-sustaining Proliferation and Survival in Pulmonary Hypertension http://www.phcentral.org/news/6210 http://www.atsjournals.org/doi/abs/10.1164/rccm.201510-2003OC#.VzRYlNQrLWd May 12, 2016 ]]> Chronic thromboembolic pulmonary hypertension - a diagnostic and therapeutic update. http://www.phcentral.org/news/6209 http://www.ncbi.nlm.nih.gov/pubmed/27128884 May 11, 2016 AVEO Announces Filing of Provisional Patent Applications for AV-353, a Notch 3-Specific Inhibitor Antibody for PAH http://www.phcentral.org/news/6208 http://www.businesswire.com/news/home/20160502005345/en/AVEO-Announces-Filing-Provisional-Patent-Applications-AV-353 May 10, 2016 Older Lung Donors Raise Mortality Risk Only Slightly http://www.phcentral.org/news/6207 http://www.medscape.com/viewarticle/862727 May 9, 2016 Cumberland Pharmaceuticals Announces New Program To Develop Vasculan™ For Systemic Sclerosis http://www.phcentral.org/news/6206 http://www.streetinsider.com/Press+Releases/Cumberland+Pharmaceuticals+Announces+New+Program+To+Develop+Vasculan™+For+Systemic+Sclerosis/11546025.html May 8, 2016 Effect of dual pulmonary vasodilator therapy in pulmonary arterial hypertension associated with congenital heart disease http://www.phcentral.org/news/6205 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836289/ May 7, 2016 Aerosol-Delivered Gene Therapy Seen to Stop Vascular Remodeling in PH Study in Pigs http://www.phcentral.org/news/6204 http://pulmonaryhypertensionnews.com/2016/05/04/aerosol-delivered-gene-therapy-may-have-beneficial-effects-in-pulmonary-hypertension-treatment/ May 6, 2016 Right Ventricle Enlargement Successfully Treated in PAH Animal Model Using Ranolazine, a Heart Drug http://www.phcentral.org/news/6203 http://pulmonaryhypertensionnews.com/2016/04/20/ranolazine-prevents-rv-remodeling-in-pah-via-b-type-natriuretic-peptide/ May 5, 2016 Right Ventricle Dysfunction in PAH May Be Treated by Drug Targeting a Signaling Pathway Independent of Arterial Pressure http://www.phcentral.org/news/6202 http://pulmonaryhypertensionnews.com/2016/04/19/study-found-right-ventricle-dysfunction-in-pah-might-be-treated-independently-of-arterial-pressure/ May 4, 2016 Tissue-engineered artificial lung that mimics the response of the human lung to drugs, toxins and other agents http://www.phcentral.org/news/6201 http://medicalxpress.com/news/2016-04-tissue-engineered-artificial-lung-mimics-response.html May 4, 2016 Pediatric research: Researchers now think fibrosis can be reversed http://www.phcentral.org/news/6200 http://www.dispatch.com/content/stories/science/2016/04/24/01-pediatric-research-researchers-now-think-fibrosis-can-be-reversed.html May 3, 2016 PAH Is Rising in Elderly, and So Are Challenges in Correctly Diagnosing and Treating Their Disease http://www.phcentral.org/news/6199 http://pulmonaryhypertensionnews.com/2016/04/27/pah-in-elderly-a-challenging-diagnosis-requiring-expert-opinion/ May 3, 2016 ]]> Special training strengthens heart of patients with pulmonary hypertension: study http://www.phcentral.org/news/6198 http://www.shanghaidaily.com/article/article_xinhua.aspx?id=328152 May 2, 2016 Scientists Discover Shared Genes in COPD and IPF, Pointing to Potential Drug Development http://www.phcentral.org/news/6196 http://lungdiseasenews.com/2016/04/28/scientists-discover-shared-genes-copd-ipf-pointing-potential-drug-development/ May 2, 2016 Yoga Shows Promise as Way to Improve Quality of Life in Pulmonary Arterial Hypertension (PAH) Patients http://www.phcentral.org/news/6197 https://globenewswire.com/news-release/2016/04/28/834526/10162239/en/Yoga-Shows-Promise-as-Way-to-Improve-Quality-of-Life-in-Pulmonary-Arterial-Hypertension-PAH-Patients.html May 1, 2016 ]]> Drugs for Pulmonary Arterial Hypertension: Comparative Efficacy, Safety, and Cost-Effectiveness http://www.phcentral.org/news/6194 http://www.ncbi.nlm.nih.gov/books/NBK355844/pdf/Bookshelf_NBK355844.pdf May 1, 2016 Gene therapy halts pulmonary hypertension progression in large animal pre-clinical study http://www.phcentral.org/news/6195 http://medicalxpress.com/news/2016-04-gene-therapy-halts-pulmonary-hypertension.html April 30, 2016 TGA approves combination treatment for PAH treatment http://www.phcentral.org/news/6193 http://www.thepharmaletter.com/article/tga-approves-combination-treatment-for-pah-treatment April 30, 2016 Memorial Hermann Heart & Vascular Institute-Texas Medical Center Launches Lung Transplant Program http://www.phcentral.org/news/6192 http://www.prnewswire.com/news-releases/memorial-hermann-heart--vascular-institute-texas-medical-center-launches-lung-transplant-program-300248732.html April 29, 2016