PHCentral RSS - rss http://phcentral.org FIRE feed Sat, 25 Apr 2015 14:04:45 GMT Diastolic Pulmonary Gradient does not Predict Survival in Pulmonary Hypertension due to Left Heart Failure http://www.phcentral.org/news/5704 https://www.acc.org/latest-in-cardiology/articles/2015/04/14/10/07/diastolic-pulmonary-gradient-does-not-predict-survival-in-pulmonary-hypertension-due-to-left-heart-failure?w_nav=LC April 26, 2015 Salidroside Decreases Lung Pathology Associated with Pulmonary Arterial Hypertension http://www.phcentral.org/news/5703 http://pulmonaryhypertensionnews.com/2015/04/21/salidroside-decreases-lung-pathology-associated-pulmonary-arterial-hypertension/ April 26, 2015 Journal of Molecular and Cellular Cardiology.]]> Serology Helps Pinpoint Type of Scleroderma http://www.phcentral.org/news/5702 http://www.medpagetoday.com/Rheumatology/GeneralRheumatology/51159 April 25, 2015 The Implantable Pediatric Artificial Lung http://www.phcentral.org/news/5701 http://www.ncbi.nlm.nih.gov/pubmed/25905495 April 24, 2015 DiscoveryBioMed, Inc. is developing a novel “dual action” small molecule monotherapy for all cystic fibrosis (CF) patients http://www.phcentral.org/news/5693 http://www.businesswire.com/news/home/20150414005091/en/DiscoveryBioMed-developing-“dual-action”-small-molecule-monotherapy#.VTJBW4GuqSo April 24, 2015 Early Decline in 6-minute Walk Test Distance Predicts Pulmonary Arterial Hypertension Deterioration http://www.phcentral.org/news/5696 http://pulmonaryhypertensionnews.com/2015/04/17/early-decline-6-minute-walk-test-distance-predicts-pulmonary-arterial-hypertension-deterioration/ April 23, 2015 Johns Hopkins iOS app helps clinicians learn to diagnose sleep disorders http://www.phcentral.org/news/5692 http://www.technologytell.com/apple/148697/johns-hopkins-ios-app-helps-clinicians-learn-diagnose-sleep-disorders/ April 23, 2015 Diet makes the differenice in broiler chicken - PH http://www.phcentral.org/news/5700 http://www.ncbi.nlm.nih.gov/pubmed/25900413 April 23, 2015 In a trial, different nutrition was tried and it turned out, that a protein-reduced and antioxidant enriched (co-encym Q10 and vitamine E) diet reduced death by PH in these animal. This shows at least, that nutrition could make a difference. If this would also apply to humans had would be difficult to find out.
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Uptravi Boost to Pulmonary Arterial Hypertension (PAH) Market to Be Game Changer: Transparency Market Research http://www.phcentral.org/news/5691 http://www.businesswire.com/news/home/20150413005563/en/Uptravi-Boost-Pulmonary-Arterial-Hypertension-PAH-Market#.VTJAm4GuqSo April 22, 2015 Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat. http://www.phcentral.org/news/5699 http://circres.ahajournals.org/content/early/2015/03/12/CIRCRESAHA.116.305265.abstract April 22, 2015 [..]
Trial results suggest a major role for iron in pulmonary vascular homeostasis and support the clinical evaluation of iron replacement in patients with pulmonary hypertension.]]>
Salidroside Herb Found To Reduce Chronic Hypoxia-induced PAH http://www.phcentral.org/news/5698 http://lungdiseasenews.com/2015/04/20/salidroside-herb-found-to-reduce-chronic-hypoxia-induced-pulmonary-arterial-hypertension/ April 21, 2015 Longterm, Multicenter, Multinational Data in PAH Presented at ISHLT Meeting http://www.phcentral.org/news/5695 http://www.marketwired.com/press-release/longterm-multicenter-multinational-data-pulmonary-arterial-hypertension-presented-ishlt-2011087.htm April 21, 2015 Promising Molecular Imaging Technology Being Tested For Pulmonary Hypertension Diagnosis http://www.phcentral.org/news/5690 The Montreal Heart Institute is currently recruiting patients for a Phase-IIc clinical trial that is evaluating the safety of PulmoBind in participants with pulmonary hypertension and its potential to detect abnormal pulmonary circulation associated within pulmonary hypertension. April 21, 2015 Submaximal exercise pulmonary gas exchange in left heart disease patients with different forms of pulmonary hypertension. http://www.phcentral.org/news/5697 http://www.onlinejcf.com/article/S1071-9164(15)00089-5/abstract April 21, 2015 High-Altitude Pulmonary Hypertension in Cattle May Unlock New Insights into Human PH http://www.phcentral.org/news/5694 http://pulmonaryhypertensionnews.com/2015/04/20/high-altitude-pulmonary-hypertension-cattle-may-unlock-new-insights-human-ph/ April 20, 2015 Does Cardiovascular Magnetic Resonance Have a Role in the Care of the Pulmonary Arterial Hypertension Patient? http://www.phcentral.org/news/5689 http://www.acc.org/latest-in-cardiology/articles/2015/04/09/08/14/does-cardiovascular-magnetic-resonance-have-a-role-in-the-care-of-the-pah-patient?w_nav=LC April 20, 2015 Researchers call for earlier PAH diagnosis and treatment http://www.phcentral.org/news/5688 http://www.news-medical.net/news/20150414/Researchers-call-for-earlier-PAH-diagnosis-and-treatment.aspx April 19, 2015 Pulmonary Hypertension Identified as Risk Factor for Cardiovascular Disease in Dialysis Patients http://www.phcentral.org/news/5687 http://pulmonaryhypertensionnews.com/2015/04/09/pulmonary-hypertension-is-a-risk-factor-for-cardiovascular-disease-in-dialysis-patients/ April 19, 2015 Kidney Research and Clinical Practice.]]> FDA Grants Reata Pharmaceuticals’ Bardoxolone Methyl Orphan Drug Designation for the Treatment of PAH http://www.phcentral.org/news/5686 http://lungdiseasenews.com/2015/04/15/fda-grants-reata-pharmaceuticals-bardoxolone-methyl-orphan-drug-designation-for-the-treatment-of-pulmonary-arterial-hypertension/ April 18, 2015 Elevated Concentrations of Circulating CXCL12? Predicts Poorer Survival in Patients with PAH http://www.phcentral.org/news/5685 http://pulmonaryhypertensionnews.com/2015/04/15/elevated-concentrations-of-circulating-cxcl12?-predicts-poorer-survival-in-patients-with-pulmonary-arterial-hypertension/ April 17, 2015 Capillary pCO2 helps determine IPAH diagnosis http://www.phcentral.org/news/5681 http://www.medwirenews.com/38/106223/Cardiology/Capillary_pCO2_helps_determine_IPAH_diagnosis.html April 16, 2015 Pulmonary hypertension and hepatic cirrhosis. http://www.phcentral.org/news/5684 http://www.ncbi.nlm.nih.gov/pubmed/25862424 April 16, 2015 EURORDIS: The Genetics Clinic of the Future http://www.phcentral.org/news/5683 http://www.eurordis.org/news/genetics-clinic-future April 15, 2015
Click headline for reading the full story behind.
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Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with PH http://www.phcentral.org/news/5682 http://www.ncbi.nlm.nih.gov/pubmed/25867313 April 15, 2015 Unpredictability remains the one constant with seasonal influenza http://www.phcentral.org/news/5680 http://www.healio.com/pediatrics/influenza/news/print/infectious-diseases-in-children/{ecb14d58-63ee-422a-85fb-1b7ae76e5b47}/unpredictability-remains-the-one-constant-with-seasonal-influenza April 15, 2015 Lung Cells Can Regenerate Themselves, Finding Could Bring New Disease Cures http://www.phcentral.org/news/5679 Lung tissue is better at regenerating itself after injury than previously thought, a discovery that could improve the treatment of some lung and breathing disorders, researchers say. April 14, 2015 Inhaled nitric oxide therapy and risk of renal dysfunction: a systematic review and meta-analysis of randomized trials http://www.phcentral.org/news/5677 http://7thspace.com/headlines/506075/inhaled_nitric_oxide_therapy_and_risk_of_renal_dysfunction_a_systematic_review_and_meta_analysis_of_randomized_trials.html April 13, 2015
The authors suggest monitoring renal function during iNO therapy, and that future trials of iNO should evaluate renal safety.
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Oestrogen receptor alpha in pulmonary hypertension http://www.phcentral.org/news/5678 http://cardiovascres.oxfordjournals.org/content/early/2015/04/06/cvr.cvv106 April 12, 2015 Pulmonary hypertension and pregnancy: The experience of a tertiary institution over 15 years http://www.phcentral.org/news/5676 http://www.annals.in/article.asp?issn=0971-9784;year=2015;volume=18;issue=2;spage=153;epage=160;aulast=Monagle April 11, 2015 Rheumatoid Arthritis Related Diseases Have Similar Survival Rates http://www.phcentral.org/news/5675 http://www.hcplive.com/news/Rheumatoid-Arthritis-Related-Diseases-Have-Similar-Survival-Rates April 11, 2015 Respirology.]]> Ongoing Clinical Trial Testing Molecular Imaging Agent for Pulmonary Hypertension Diagnosis http://www.phcentral.org/news/5674 http://lungdiseasenews.com/2015/04/08/ongoing-clinical-trial-testing-molecular-imaging-agent-for-pulmonary-hypertension-diagnosis/ April 10, 2015 Patients Undergoing Hemodialysis Have Higher Prevalence of Pulmonary Hypertension and Heart Disease http://www.phcentral.org/news/5673 http://lungdiseasenews.com/2015/04/09/patients-undergoing-hemodialysis-have-higher-prevalence-of-pulmonary-hypertension-and-heart-disease/ April 9, 2015 Promising Molecular Imaging Technology Being Tested For Pulmonary Hypertension Diagnosis http://www.phcentral.org/news/5672 http://pulmonaryhypertensionnews.com/2015/04/08/ongoing-clinical-trial-tests-the-safety-of-pulmobind-for-molecular-imaging-of-pulmonary-hypertension/ April 8, 2015 Actavis Seeks FDA Approval for Generic Letairis to Treat PAH Patients http://www.phcentral.org/news/5671 http://pulmonaryhypertensionnews.com/2015/04/07/actavis-seeks-fda-approval-for-generic-letairis-to-treat-pah-patients/ April 7, 2015 Aurobindo Pharma gets USFDA nod for Sildenafil injection http://www.phcentral.org/news/5670 http://economictimes.indiatimes.com/industry/healthcare/biotech/aurobindo-pharma-gets-usfda-nod-for-sildenafil-injection/articleshow/46805882.cms April 6, 2015 MySleep101 App Addresses Sleep Disorders Associated With PH, Other Conditions http://www.phcentral.org/news/5669 http://pulmonaryhypertensionnews.com/2015/04/03/mysleep101-app-addresses-sleep-disorders-associated-with-ph-other-conditions/ April 5, 2015 Heterogeneous Gene Expression Signatures Correspond to Distinct Lung Pathologies and Biomarkers of Disease Severity in Idiopathic Pulmonary Fibrosis http://www.phcentral.org/news/5668 http://www.medscape.com/viewarticle/840120 April 5, 2015 Ongoing Clinical Trial Testing Tadalafil for Pulmonary Hypertension Due to COPD http://www.phcentral.org/news/5667 http://pulmonaryhypertensionnews.com/2015/04/02/ongoing-clinical-trial-on-tadalafil-for-pulmonary-hypertension-due-to-chronic-obstructive-pulmonary-disease-copd/ April 4, 2015 COPD Affects Nearly 16 Million Americans, Researchers Report http://www.phcentral.org/news/5666 http://www.medscape.com/viewarticle/842239 April 4, 2015 Surrogate Marker Has to Suffice for Rare Disease, FDA Says http://www.phcentral.org/news/5665 http://www.medscape.com/viewarticle/842090 April 3, 2015 Pulmonary Hypertension And Advanced HF Included In The New Guidelines For Pediatric Cardiology http://www.phcentral.org/news/5664 http://www.doctorpulse.co/?p=4177 April 2, 2015 Bellerophon Reports 2014 Operational Results http://www.phcentral.org/news/5663 http://globenewswire.com/news-release/2015/03/31/720509/10126975/en/Bellerophon-Reports-2014-Full-Year-Financial-and-Operational-Results.html April 1, 2015 Actelion Receives Japan Marketing Approval For Opsumit For Pulmonary Arterial Hypertension http://www.phcentral.org/news/5662 http://pulmonaryhypertensionnews.com/2015/03/31/actelion-receives-japan-marketing-approval-for-opsumit-for-pulmonary-arterial-hypertension/ April 1, 2015 Elusive Origin of Pulmonary Hypertension Uncovered http://www.phcentral.org/news/5661 http://www.healthcanal.com/blood-heart-circulation/blood-pressure/61846-elusive-origin-of-pulmonary-hypertension-uncovered.html March 31, 2015 ..
In studies that have spanned nearly eight years of work, Chan and his colleagues found that specific disruptions in mitochondria, the powerhouses of cells, lead to alterations of energy production, or metabolism, of blood vessels of the lungs. ISCU is a critical human protein that generates factors called iron-sulfur clusters essential for normal mitochondrial function.]]>
Serial Risk Score For Pulmonary Arterial Hypertension Helps Predict Disease Outcomes http://www.phcentral.org/news/5660 http://lungdiseasenews.com/2015/03/27/serial-risk-score-in-pulmonary-arterial-hypertension-helps-predict-disease-outcomes/ March 31, 2015 Researchers Find Pulmonary Hypertension Drug Sildenafil Has No Significant Impact on Cardiac Function http://www.phcentral.org/news/5659 http://lungdiseasenews.com/2015/03/30/researchers-find-pulmonary-hypertension-drug-sildenafil-has-no-significant-impact-on-cardiac-function/ March 30, 2015 Why Dietary Cholesterol Is No Longer Enemy Number One http://www.phcentral.org/news/5658 http://www.medscape.com/viewarticle/841486 March 29, 2015 Observing Alterations on Right Side of Heart Reveals COPD-Related PH Best http://www.phcentral.org/news/5657 http://pulmonaryhypertensionnews.com/2015/03/17/copd-related-ph-is-better-detected-looking-at-right-sided-heart-alterations/ March 29, 2015 Egyptian Journal of Chest Diseases and Tuberculosis suggest that Pulmonary hypertension (PH) in patients with Chronic Obstructive Pulmonary Disease (COPD) is a common co-morbidity along with right sided cardiac changes. Based on the findings, the researchers suggest that Echocardiography should be used with caution during assessment of pulmonary artery systolic pressure (PASP). In the study, COPDPH patients were also found to have worse prognosis than COPD patients without PH.]]> Clinical Pharmacology of Endothelin Receptor Antagonists Used in the Treatment of PAH http://www.phcentral.org/news/5656 http://www.medscape.com/viewarticle/840993 March 28, 2015 Iron Homeostasis and Pulmonary Hypertension http://www.phcentral.org/news/5655 http://circres.ahajournals.org/content/early/2015/03/12/CIRCRESAHA.116.305265.abstract March 28, 2015 Researchers Uncover a Potential Non-invasive Test for Certain Types of Pulmonary Hypertension http://www.phcentral.org/news/5654 http://pulmonaryhypertensionnews.com/2015/03/26/researchers-uncover-a-potential-non-invasive-test-for-certain-types-of-pulmonary-hypertension/ March 27, 2015 Pulmonary arterial hypertension associated with chronic active Epstein-Barr virus infection. http://www.phcentral.org/news/5653 http://www.ncbi.nlm.nih.gov/pubmed/25809637 March 27, 2015